WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:antigen processing and presentation of exogenous peptide antigen       ID:GO:0002478
C=168; O=14; E=0.37; R=38.10; rawP=1.58e-19; adjP=5.07e-17
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
12  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:biological process       Name:antigen processing and presentation of exogenous antigen       ID:GO:0019884
C=170; O=14; E=0.37; R=37.65; rawP=1.87e-19; adjP=5.07e-17
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
12  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:biological process       Name:exogen       ID:GO:0042638
C=179; O=14; E=0.39; R=35.76; rawP=3.92e-19; adjP=7.08e-17
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
12  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:biological process       Name:antigen processing and presentation of peptide antigen       ID:GO:0048002
C=186; O=14; E=0.41; R=34.41; rawP=6.79e-19; adjP=7.77e-17
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
12  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:biological process       Name:immune system process       ID:GO:0002376
C=1792; O=26; E=3.92; R=6.63; rawP=7.17e-19; adjP=7.77e-17
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
2  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
3  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
4  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
5  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
6  ENSG00000143153 NA ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 481 ENSG00000143153
7  ENSG00000090554 NA FLT3LG fms-related tyrosine kinase 3 ligand 2323 ENSG00000090554
8  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
9  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
10  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
11  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
12  ENSG00000112149 NA CD83 CD83 molecule 9308 ENSG00000112149
13  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
14  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
15  ENSG00000131203 NA IDO1 indoleamine 2,3-dioxygenase 1 3620 ENSG00000131203
16  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
17  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
18  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
19  ENSG00000124508 NA BTN2A2 butyrophilin, subfamily 2, member A2 10385 ENSG00000124508
20  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
21  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
22  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
23  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
24  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
25  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
26  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:hair follicle maturation       ID:GO:0048820
C=193; O=14; E=0.42; R=33.16; rawP=1.15e-18; adjP=1.04e-16
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
12  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:biological process       Name:immune response       ID:GO:0006955
C=1071; O=22; E=2.34; R=9.39; rawP=2.71e-18; adjP=2.10e-16
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
2  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
3  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
4  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
5  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
6  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
7  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
9  ENSG00000112149 NA CD83 CD83 molecule 9308 ENSG00000112149
10  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
11  ENSG00000131203 NA IDO1 indoleamine 2,3-dioxygenase 1 3620 ENSG00000131203
12  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
13  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
14  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
15  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
16  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
17  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
18  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
19  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
20  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
21  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
22  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:interferon-gamma-mediated signaling pathway       ID:GO:0060333
C=75; O=11; E=0.16; R=67.05; rawP=3.54e-18; adjP=2.40e-16
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000117228 NA GBP1 guanylate binding protein 1, interferon-inducible 2633 ENSG00000117228
5  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
6  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
7  ENSG00000140853 NA NLRC5 NLR family, CARD domain containing 5 84166 ENSG00000140853
8  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
9  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
10  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
11  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347


Database:biological process       Name:antigen processing and presentation       ID:GO:0019882
C=216; O=14; E=0.47; R=29.63; rawP=5.71e-18; adjP=3.44e-16
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
12  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:biological process       Name:anatomical structure maturation       ID:GO:0071695
C=218; O=14; E=0.48; R=29.36; rawP=6.51e-18; adjP=3.53e-16
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
6  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
7  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
8  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
9  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
10  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
11  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
12  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
13  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
14  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:molecular function       Name:       ID:GO:0032395
C=12; O=3; E=0.02; R=159.21; rawP=7.42e-07; adjP=5.19e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252


Database:molecular function       Name:MHC class I receptor activity       ID:GO:0032393
C=19; O=3; E=0.03; R=100.55; rawP=3.24e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
2  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
3  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642


Database:molecular function       Name:chemokine activity       ID:GO:0008009
C=47; O=3; E=0.07; R=40.65; rawP=5.27e-05; adjP=0.0012
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
2  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
3  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248


Database:molecular function       Name:chemokine receptor binding       ID:GO:0042379
C=56; O=3; E=0.09; R=34.12; rawP=8.93e-05; adjP=0.0016
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
2  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
3  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248


Database:molecular function       Name:cytokine activity       ID:GO:0005125
C=207; O=4; E=0.33; R=12.31; rawP=0.0003; adjP=0.0042
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
2  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
3  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
4  ENSG00000090554 NA FLT3LG fms-related tyrosine kinase 3 ligand 2323 ENSG00000090554


Database:molecular function       Name:threonine-type endopeptidase activity       ID:GO:0004298
C=21; O=2; E=0.03; R=60.65; rawP=0.0005; adjP=0.0050
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
2  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065


Database:molecular function       Name:threonine-type peptidase activity       ID:GO:0070003
C=21; O=2; E=0.03; R=60.65; rawP=0.0005; adjP=0.0050
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
2  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065


Database:molecular function       Name:MHC protein binding       ID:GO:0042287
C=24; O=2; E=0.04; R=53.07; rawP=0.0006; adjP=0.0053
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
2  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:molecular function       Name:receptor binding       ID:GO:0005102
C=1211; O=7; E=1.90; R=3.68; rawP=0.0020; adjP=0.0156
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
2  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
3  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
6  ENSG00000090554 NA FLT3LG fms-related tyrosine kinase 3 ligand 2323 ENSG00000090554
7  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:molecular function       Name:G-protein coupled receptor binding       ID:GO:0001664
C=199; O=3; E=0.31; R=9.60; rawP=0.0036; adjP=0.0252
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
2  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
3  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248


Database:cellular component       Name:MHC protein complex       ID:GO:0042611
C=38; O=11; E=0.08; R=137.12; rawP=7.87e-22; adjP=7.48e-20
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
6  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
7  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
8  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
9  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
10  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
11  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:MHC class II protein complex       ID:GO:0042613
C=16; O=7; E=0.03; R=207.24; rawP=1.13e-15; adjP=5.37e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
5  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
6  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
7  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574


Database:cellular component       Name:ER to Golgi transport vesicle membrane       ID:GO:0012507
C=37; O=8; E=0.08; R=102.42; rawP=6.32e-15; adjP=2.00e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
5  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
6  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
7  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:ER to Golgi transport vesicle       ID:GO:0030134
C=41; O=8; E=0.09; R=92.43; rawP=1.56e-14; adjP=3.70e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
5  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
6  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
7  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:integral to lumenal side of endoplasmic reticulum membrane       ID:GO:0071556
C=28; O=7; E=0.06; R=118.42; rawP=1.15e-13; adjP=2.19e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
5  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
6  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
7  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:transport vesicle membrane       ID:GO:0030658
C=76; O=8; E=0.16; R=49.86; rawP=2.92e-12; adjP=4.62e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
5  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
6  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
7  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:endocytic vesicle membrane       ID:GO:0030666
C=93; O=8; E=0.20; R=40.75; rawP=1.54e-11; adjP=2.09e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
5  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
6  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
7  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:integral to endoplasmic reticulum membrane       ID:GO:0030176
C=106; O=8; E=0.22; R=35.75; rawP=4.46e-11; adjP=5.30e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
5  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
6  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
7  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:intrinsic to endoplasmic reticulum membrane       ID:GO:0031227
C=123; O=8; E=0.26; R=30.81; rawP=1.49e-10; adjP=1.57e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
2  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
3  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
4  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
5  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
6  ENSG00000204267 NA TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6891 ENSG00000204267 ENSG00000250264
7  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865
8  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582


Database:cellular component       Name:endosome membrane       ID:GO:0010008
C=315; O=10; E=0.66; R=15.04; rawP=6.66e-10; adjP=5.33e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000204257 NA HLA-DMA major histocompatibility complex, class II, DM alpha 3108 ENSG00000204257
2  ENSG00000231389 NA HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3113 ENSG00000231389
3  ENSG00000204287 NA HLA-DRA major histocompatibility complex, class II, DR alpha 3122 ENSG00000204287
4  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
5  ENSG00000204592 NA HLA-E major histocompatibility complex, class I, E 3133 ENSG00000204592
6  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
7  ENSG00000242574 NA HLA-DMB major histocompatibility complex, class II, DM beta 3109 ENSG00000242574
8  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
9  ENSG00000204252 NA HLA-DOA major histocompatibility complex, class II, DO alpha 3111 ENSG00000204252
10  ENSG00000223865 NA HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115 ENSG00000223865




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).